Integration of Metabolic and Gene Regulatory Networks Modulates the C. elegans Dietary Response; Interspecies Systems Biology Uncovers Metabolites Affecting C. elegans Gene Expression and Life History Traits

Cell. 2013 Mar 28;153(1):253-66.

Emma Watson, Lesley T MacNeil, H Efsun Arda, Lihua Julie Zhu, Albertha J M Walhout.

Cell. 2014 Feb 13;156(4):759-70.

Emma Watson, Lesley T MacNeil, Ashlyn D Ritter, L Safak Yilmaz, Adam P Rosebrock, Amy A Caudy, Albertha J M Walhout.

線虫が早く育つが繁殖能と寿命が減少する餌（Comamonas aquatica）を与えると起こる遺伝子発現変化やその分子機構を解析。餌のビタミンB12が重要。筆頭著者のエマ・ワトソンは名前が名前だけに有名（業績もすごい）。UMMSのWalhout研。2013/2014年。

https://www.cell.com/cell/fulltext/S0092-8674(13)00284-5

https://www.cell.com/fulltext/S0092-8674(14)00141-X